Can I take Shiitake and White button together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
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There are no known harmful interactions between shiitake mushrooms and white button mushrooms when eaten as part of a normal diet.
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Why this happens
Both are edible fungi that are processed by the body as food. They do not interfere with each other's absorption or breakdown in the body.
What you should do
It is safe to consume these mushrooms together. However, if you are taking medicinal shiitake supplements (which are much more concentrated than food), always check with a healthcare professional, especially if you are on blood-thinning medication.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published
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