Amisulpride

About amisulpride

What is amisulpride used for?

Amisulpride is a type of antipsychotic used to treat schizophrenia. These medicines work on the balance of chemical substances in the brain.

You will have been prescribed amisulpride to relieve the symptoms of schizophrenia, a mental health problem which affects your thoughts, feelings or behaviours.

Symptoms of schizophrenia include hearing, seeing or sensing things that are not real, having mistaken beliefs, and feeling unusually suspicious. Amisulpride will help to ease these symptoms.

Side effects of amisulpride

The most common side effects of amisulpride are:

• Feeling shaky or restless.

• Feeling dizzy or sleepy.

• Feeling light-headed when you stand up.

• Dry mouth.

• Feeling sick (nausea).

• Being sick (vomiting).

• Constipation.

• Unusual muscle movements.

You may also experience other side effects including:

• Weight gain.

• Trouble sleeping.

• Feeling anxious or agitated.

• Changes in sexual ability.

• Breast pain.

• Breast enlargement in men.

• Abnormal production of breast milk.

• Menstrual problems.

• Producing more saliva than usual.

You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

How to manage amisulpride side effects

If you experience any other symptoms which you think may be due to the medicine, speak with your doctor or pharmacist for further advice.

Who should not take amisulpride?

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking amisulpride it is important that your doctor knows:

• If you are pregnant or breastfeeding.

• If you have a heart condition or blood vessel disease.

• If you have liver, kidney, or prostate problems.

• If you have any problems with your breathing.

• If you have any of the following: epilepsy, depression, Parkinson's disease, raised pressure in your eye (glaucoma) or myasthenia gravis - a condition which causes muscle weakness.

• If you have ever had yellowing of your skin or of the whites of your eyes (jaundice) or a blood disorder.

• If you have a tumour on your adrenal gland (a condition called phaeochromocytoma), or if you have been told you have 'a prolactin-dependent tumour'.

• If you have had an allergic reaction to a medicine.

• If you are taking or using any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines.

How to take amisulpride

• Read the manufacturer's printed information leaflet from inside the pack. It will give you more information about amisulpride and it will also provide you with a full list of the side effects which you may experience from taking it.

• Your dose will be adjusted to suit your condition so take amisulpride exactly as your doctor tells you to. It is usual to be prescribed two doses to take each day (in the morning and evening), although lower doses can be taken just once a day.

  • Your dose will be printed on the label of your pack to remind you about what the doctor said to you.

• Try to get into the habit of taking your doses at the same times each day, as this will help you avoid missing any. If possible, take your doses before a meal.

• If you have been given tablets, these are best swallowed with a drink of water. If you have any difficulties swallowing, let your doctor know so that you can be prescribed a liquid medicine instead.

• If you have been given liquid medicine, make sure you understand how to use the dose syringe to measure out your doses. Some syringes measure out the dose in milligrams (mg), others in millilitres (ml).

  • Put the measuring syringe into the bottle and draw back the plunger of the syringe to the graduation mark equal to the amount of solution that corresponds to your dose.

• Swallow the liquid solution with a non-alcoholic drink. If you are in any way unsure about measuring out your dose using the syringe, you can ask your local pharmacist to show you what to do.

• If you forget to take a dose, take it as soon as you remember unless it is nearly time for your next dose, in which case leave out the missed dose. Do not take two doses together to make up for a missed dose.

Getting the most from your treatment

• You will need to have some tests from time to time as your treatment will require careful monitoring to make sure that you get the best possible benefit from amisulpride.

  • Remember to keep your regular doctor's appointments so that your progress can be checked.

• Treatment with amisulpride is usually long-term unless you experience an adverse effect. Keep taking it unless your doctor tells you otherwise.

  • Stopping amisulpride suddenly can cause problems so your doctor may want you to reduce your dose gradually if this becomes necessary.

• If you drink alcohol, ask your doctor for advice about drinking while you are on amisulpride. Alcohol increases the risk of side effects so it is generally best avoided.

• If you have diabetes you may need to check your blood glucose more frequently, as amisulpride may affect the levels of sugar in your blood. Your doctor will advise you about this.

• Some medicines similar to amisulpride can cause the skin to become more sensitive to sunlight than normal. It may be advisable to use a sunscreen in bright sunlight until you know how your skin reacts.

• If you are having an operation, tell the person carrying out the treatment which medicines you are taking. This is important because amisulpride may interfere with any anaesthetic you receive.

• If you buy or take any 'over-the-counter' medicines, check with a pharmacist that they are suitable for you to take with amisulpride.

How to store amisulpride

• Keep all medicines out of the reach and sight of children.

• Store in a cool, dry place, away from direct heat and light.

• Check the expiry date on the bottle. Do not use any medicine beyond its expiry date.

Important information about all medicines

Frequently asked questions

Is amisulpride a mood stabiliser?

Amisulpride is not classed as a mood stabiliser. It is an antipsychotic medicine, mainly used to treat symptoms of schizophrenia and sometimes depression at lower doses

How quickly does amisulpride work?

Amisulpride does not work immediately. Some symptoms may improve in a few days, but it usually takes several weeks to feel the full effect. Your doctor will check your progress after a few weeks.