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Azelastine eye drops

Optilast

Azelastine drops relieve eye itching and redness associated with allergies.

It is usual to use the drops twice each day, although they can be used up to four times a day for severe symptoms.

When first put in, eye drops can cause blurred vision. Wait until this clears before you drive and before you use tools or machines.

At a glance

  • Azelastine eye drops are antihistamine drops used for allergic conjunctivitis symptoms like itchy, red, or watery eyes.

  • They work by blocking histamine, a chemical released during allergic reactions.

  • Common side effects include stinging, burning, mild irritation, and temporary blurred vision.

  • Do not wear soft contact lenses unless advised by your doctor, as the drops may irritate them.

  • If symptoms do not improve within 2 days or get worse, seek medical advice.

  • Eye drops only last for four weeks once opened due to the risk of eye infections.

  • Seek medical advice if you notice a rash, swelling, or increased itching around your eyes.

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Overview

Type of medicine

Antihistamine eye drops

Used for

To relieve the symptoms of allergic conjunctivitis

Also called

Optilast®

Available as

Eye drops

Azelastine eye drops are used to treat the symptoms of allergic conjunctivitis, including itchy, red, watery, and irritated eyes.

They are antihistamine eye drops that help relieve eye allergy symptoms caused by allergens such as pollen, pet dander, and house dust mites.

Azelastine eye drops can be used for both seasonal allergic conjunctivitis (hay fever eye symptoms) and perennial allergic conjunctivitis, which causes symptoms throughout the year.

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Azelastine eye drops work by blocking the action of histamine, a chemical released by the body during an allergic reaction.

When allergens come into contact with the eyes, histamine is released, causing inflammation and allergy symptoms. By preventing histamine from attaching to its receptors, azelastine eye drops help reduce itching, redness, watering, and discomfort.

The most common side effects of azelastine eye drops are:

  • Stinging.

  • Burning.

  • Mild irritation.

  • Brief blurred vision.

A full list of side effects can be found in the manufacturers leaflet. Speak with your doctor or pharmacist if any side effects continue or become troublesome.

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Common azelastine side effects

What can I do if I experience this?

Mild eye irritation (such as stinging)

This usually disappears within a few minutes of using the eye drops

Occasionally people can be allergic to eye drops, particularly when the eye drops contain a preservative. If you notice a rash around your eyes, or any swelling or increased itching, stop using the drops and contact a doctor for advice.

If you experience any other symptoms which you think may be due to the eye drops, speak with your doctor or pharmacist for further advice.

To make sure this is the right treatment for you, before you start using the eye drops it is important that your doctor knows:

  • If you wear soft contact lenses.

  • If you are pregnant or breastfeeding. (Although azelastine is not known to be harmful to babies, it is still important that you tell your doctor if you are expecting or breastfeeding a baby.)

  • If you have ever had an allergic reaction to an antihistamine, or to any other eye drops.

  1. Wash your hands before you use the drops.

  2. Remove the cap.

  3. Tilt your head back a little, and then pull the lower lid of your eye out to form a pocket between your eye and the lower eyelid.

  4. Hold the bottle upside down near to your eye. Try not to touch your eye as you do this.

  5. Apply sufficient pressure to the bottle to release one drop into your eye. Only use a second drop if the first drop missed going into your eye.

  6. Close your eye for a minute or two, and press gently on the side of your nose where the corner of your eye meets your nose. This helps to stop the drop from draining away and keeps it in your eye.

  7. Repeat the process in your other eye.

  8. Replace the cap.

  • Read the leaflet first. It explains how to use the drops and lists possible side effects.

  • Use twice daily. Usually morning and evening. In severe cases, up to 4 times daily if advised.

  • Expect brief blurred vision. This is normal after use. Wait until your vision clears before driving or using tools.

  • Keep the dropper clean. Do not touch your eye, fingers, or any surface with the bottle tip.

  • Space out other eye drops. Leave 5-10 minutes between different eye drops to avoid washing them out.

  • Use for the recommended duration only. Do not use for more than 6 weeks unless your doctor advises otherwise.

  • See a doctor if no improvement. If symptoms do not improve within 2 days or get worse, seek medical advice.

  • Avoid soft contact lenses. Do not wear them unless your doctor says it is safe, as the drops may irritate lenses.

  • Keep all medicines out of the reach and sight of children.

  • Store in a cool, dry place, away from direct heat and light.

  • Eye drops only keep for four weeks once the bottle has been opened - do not use the drops if the bottle has been open for longer than this. This helps to prevent the risk of eye infections.

How quickly do azelastine eye drops work?

Azelastine eye drops usually start to relieve allergy symptoms such as itchy and watery eyes within 10-30 minutes. Full relief may improve with regular use as directed.

Can I use azelastine eye drops every day?

Yes. Azelastine eye drops are designed for regular daily use during allergy flare-ups. Do not exceed the prescribed frequency or use longer than advised by your doctor.

Can I use azelastine eye drops with antihistamine tablets?

Yes. Azelastine eye drops can usually be used alongside oral antihistamines. This combination may provide better relief for moderate to severe allergy symptoms.

Important information about all medicines

If you buy any medicines check with a pharmacist that they are safe to use with your other medicines.

Never use more than the prescribed dose.

If you suspect that someone has swallowed some of this medicine by accident, contact the accident and emergency department of your local hospital for advice.

If you are having an operation or dental treatment, tell the person carrying out the treatment which medicines you are using.

This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.

Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.

If you have any questions about this medicine ask your pharmacist.

MHRA - Reporting adverse reactions

Report suspected side effects to medicines, vaccines, e-cigarettes, medical device incidents, defective or falsified (fake) products to the Medicines and Healthcare products Regulatory Agency to ensure safe and effective use.

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Further reading and references

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About the authorView full bio

Author image

Michael Stewart, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewerView full bio

Author image

Dr Colin Tidy, MRCGP

General Practitioner, Medical Author

MBBS, MRCGP, MRCP (Paediatrics), DCH

Dr Colin Tidy is an NHS Doctor, based in Oxfordshire.

Article history

The information on this page is written and peer reviewed by qualified clinicians.

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