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Ciprofibrate for hyperlipidaemia

Take one (100 mg) tablet daily.

Some lifestyle changes will also help to reduce your lipid level - eat healthy food, stop smoking, increase the exercise you take, and reduce the amount of salt in your diet.

If you develop any unusual aches and pains in your muscles, contact your doctor for advice.

At a glance

  • Ciprofibrate is a medicine for adults that helps lower high levels of fats in your blood.

  • Taking ciprofibrate regularly helps prevent heart disease, stroke, and circulation problems.

  • The usual dose is one 100 mg tablet once a day, with or without food.

  • You will need regular blood tests during the first year of treatment to check your liver.

  • Common side-effects include indigestion, headaches, and muscle aches.

Continue reading below

About ciprofibrate

Type of medicine

A lipid-regulating medicine commonly known as a fibrate

Used for

Hyperlipidaemia (in adults)

Available as

Tablets

Lipid is another word for fat. Cholesterol and triglycerides are types of lipid. When the concentration of lipids in your blood is too high, it is called hyperlipidaemia. Lipids are made naturally in our bodies and are also absorbed from the food we eat. If the levels of lipids are too high, the excess fat is deposited on to the walls of our blood vessels. This can lead to patches like small fatty lumps developing within the lining of some blood vessels. These patches can reduce the flow of blood, and lead to heart disease, stroke, and blood circulation problems.

High levels of lipids do not make people feel ill, but they can cause the problems mentioned above if left untreated. By lowering the levels of fats, ciprofibrate helps to prevent these long-term heart and circulation problems. Your treatment will be more successful if you also follow the healthy lifestyle advice given by your doctor.

It is likely that you will be prescribed ciprofibrate if you have a high level of a lipid called triglyceride. It may also be given for other types of hyperlipidaemia, especially if other medicines (called statins) are not suitable for you.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking ciprofibrate it is important that your doctor knows:

  • If you are pregnant, trying for a baby or breastfeeding.

  • If you have problems with the way your kidneys work, or problems with the way your liver works.

  • If you have gallbladder problems.

  • If you have an underactive thyroid gland.

  • If you are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines.

  • If you have ever had an allergic or bad reaction to a medicine.

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  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about ciprofibrate, and it will also provide you with a full list of the side-effects which you could experience from taking it.

  • Take ciprofibrate exactly as your doctor tells you to. The usual dose is one 100 mg tablet a day.

  • You can generally take ciprofibrate at a time of day to suit you, but it is best to take your doses at the same time of day each day. This will help to remind you to take the tablets regularly.

  • You can take ciprofibrate either with or without food. Some people find it helps to swallow the tablet with a drink of water.

  • If you forget to take a dose, take it as soon as you remember. If you do not remember until the following day, leave out the forgotten dose from the previous day and take the dose that is due as normal. Do not take two doses at the same time to make up for a missed dose.

  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. You will need to have regular blood tests during the first year of your treatment with ciprofibrate. These are to check that your liver stays healthy.

  • Your doctor will give you advice about eating a healthy diet, avoiding drinking too much alcohol, reducing the amount of salt in your diet, stopping smoking, and taking regular exercise. Following this advice will also help you to reduce your risk of developing heart and blood vessel disease.

  • Treatment with ciprofibrate is usually long-term unless you experience an adverse effect. Continue to take the tablets unless you are advised otherwise by your doctor.

Continue reading below

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the ones associated with ciprofibrate. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common c

iprofibrate side-effects (these affect less than 1 in 10 people)


What can I do if I experience this?

Indigestion, stomach pains, feeling sick (nausea)

Stick to simple foods - avoid fatty or spicy foods

Headache

Drink plenty of water and ask your pharmacist to recommend a suitable painkiller. If the headaches continue, speak with your doctor

Diarrhoea

Drink plenty of water to replace lost fluids

Balance problems, feeling dizzy or tired

Do not drive and do not use tools or machines while affected

Muscle aches or pains

Let your doctor know about this

Hair loss, skin rash

If troublesome, speak with your doctor

If you experience any other symptoms which you think may be due to the tablets, speak with your doctor or pharmacist for further advice.

  • Keep all medicines out of the reach and sight of children.

  • Store in a cool, dry place, away from direct heat and light.

Important information about all medicines

Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.

This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.

If you buy any medicines, check with a pharmacist that they are safe to take with your other medicines.

If you are having an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking.

Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.

If you have any questions about this medicine ask your pharmacist.

Report side effects to a medicine or vaccine

If you experience side effects, you can report them online through the Yellow Card website.

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Unsure about mixing medicines?

Check for possible interactions between medicines, supplements and foods before taking them together.

Frequently asked questions

What is the main difference between ciprofibrate and statins?

Ciprofibrate is primarily prescribed if you have a high level of triglycerides, a specific type of fat. It may also be used if other medicines, like statins, are not suitable for you. This indicates that while both are lipid-regulating medicines, they might be preferred for different types of hyperlipidaemia or patient circumstances.

Will I feel sick if I stop taking ciprofibrate suddenly?

The article does not discuss withdrawal symptoms from suddenly stopping ciprofibrate. However, it advises that treatment is usually long-term and to continue taking the tablets unless your doctor advises otherwise, implying that any changes to your treatment plan should be discussed with a healthcare professional.

What should I do if I get a headache while taking ciprofibrate?

If you experience a headache, you should drink plenty of water and can ask your pharmacist to recommend a suitable painkiller. If the headaches continue or become troublesome, you should speak with your doctor.

Can ciprofibrate affect my ability to drive or operate machinery?

Yes, ciprofibrate can cause side-effects such as balance problems, feeling dizzy, or feeling tired. If you experience these effects, you should not drive or use tools or machines.

How long will I need to take ciprofibrate?

Treatment with ciprofibrate is usually long-term. You should continue to take the tablets unless your doctor advises you otherwise.

Further reading and references

Continue reading below

About the authorView full bio

Author image

Michael Stewart, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

Sid Dajani

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

Article history

The information on this page is written and peer reviewed by qualified clinicians.

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