Fexofenadine tablets
Telfast, Allevia, Allegra
Peer reviewed by Dr Colin Tidy, MRCGPLast updated by Michael Stewart, MRPharmSLast updated 19 Jun 2023
Meets Patient’s editorial guidelines
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Fexofenadine is a non-drowsy antihistamine; however, it can still cause drowsiness in a few people. Make sure your reactions are normal before you drive and before you use tools or machines.
Do not take indigestion remedies during the two hours before or the two hours after you take a fexofenadine tablet.
The most common side effects of fexofenadine are headache, dizziness, and feeling sick (nausea).
At a glance
Fexofenadine is a non-drowsy antihistamine for hay fever and hives.
It comes in tablets and works by blocking histamine.
Common side effects include headache, tiredness, and feeling sick.
Take fexofenadine before food with water, usually once daily.
Avoid indigestion remedies within 2 hours of taking fexofenadine.
Do not take with other antihistamines unless advised by a doctor.
Consult a doctor before taking if pregnant, breastfeeding, or taking other medicines.
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Overview
Type of medicine | A non-drowsy antihistamine |
Used for | Seasonal allergic rhinitis (hay fever); chronic urticaria (hives) |
Also called (UK) | Telfast®; Allevia® |
Also called (USA) | Allegra®; Mucinex® Allergy; Wal-Fex® |
Available as | Tablets; oral liquid medicine and melt-in-the-mouth tablet (USA only) |
What is fexofenadine used for?
Back to contentsFexofenadine is a type of non-drowsy antihistamine that is used to relieve symptoms of hay fever and hives.
It is available in tablet form in three strengths: 30 mg, 120 mg, and 180 mg.
30 mg strength is for treating hay fever in children aged 6-12 years.
120 mg strength is for treating adults with hay fever.
180 mg strength is for hives.
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How does fexofenadine work?
Back to contentsFexofenadine works by blocking the effects of histamine, a chemical released by the body during an allergic reaction.
When allergens such as pollen trigger the release of histamine, it can cause symptoms including sneezing, a runny or blocked nose, and red, itchy or watery eyes.
By preventing histamine from acting, fexofenadine helps relieve these allergy symptoms. It can also help reduce itching and skin rashes associated with hives.
Side effects of fexofenadine
Back to contentsCommon side effects of fexofenadine are:
Feeling sick (nausea).
Headache.
Feeling tired or dizzy.
You will find a full list in the manufacturer's information leaflet supplied with your medicine.
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How to manage fexofenadine side effects
Back to contentsThe unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any continue or become troublesome.
Common fexofenadine side effects (these affect fewer than 1 in 10 people) | What can I do if I experience this? |
Headache | Drink plenty of water and ask your pharmacist to recommend a suitable painkiller. If the headaches continue, let your doctor know |
Feeling tired or dizzy | Do not drive and do not use tools or machines until you feel better. Do not drink alcohol |
Feeling sick (nausea) | Stick to simple meals - avoid spicy foods |
If you experience any other symptoms which you think may be due to the medicine, discuss them with your doctor or pharmacist.
Who should not take fexofenadine?
Back to contentsBefore you (or your child) take fexofenadine, tell your doctor about any medical conditions or other medicines being taken, as extra care may sometimes be needed.:
If you are pregnant, trying for a baby or breastfeeding.
If you are taking or using any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines.
If you have ever had an allergic reaction to another antihistamine, or to any other medicine.
How to take fexofenadine
Back to contentsRead the leaflet provided with your medicine for more information and possible side effects.
Recommended doses of fexofenadine are:
Adults with hay fever: 120 mg once daily.
Children aged 6–12 years with hay fever: 30 mg twice daily.
Adults with hives (urticaria): 180 mg once daily.
Take fexofenadine before food if possible, with a drink of water.
Take your tablets at the same time each day to help you remember.
If you miss a dose, take the next dose at the usual time. Do not take two doses together.
Avoid taking indigestion remedies (antacids) within 2 hours before or after taking fexofenadine, as they can reduce how well it works.
Getting the most from your treatment
Back to contentsYou may only need to take fexofenadine when you have symptoms. Stop taking it once your symptoms improve, unless your doctor tells you otherwise.
Fexofenadine is usually non-drowsy, but it can make some people sleepy. If this happens, do not drive or use machinery.
Alcohol can increase side effects such as drowsiness, so drink only small amounts while taking fexofenadine.
Tell your doctor or healthcare professional you are taking fexofenadine before any operation, treatment, or allergy test.
Check with a pharmacist before taking other medicines, as some can interact with antihistamines and increase side effects.
How to store fexofenadine
Back to contentsKeep fexofenadine out of the reach and sight of children.
Store in a cool, dry place, away from direct heat and light.
Frequently asked questions
Back to contentsHow long does fexofenadine take to work?
Fexofenadine usually starts to work within 1 hour, with the full effect often felt after 2–3 hours.
How long does fexofenadine stay in your system?
Fexofenadine can remain in the body for around 24 hours, which is why it is usually taken once daily.
Can I take fexofenadine every day?
Yes, many people take fexofenadine daily during allergy seasons or for hives (chronic urticaria), but follow the advice of your doctor or pharmacist.
Can I take fexofenadine with other antihistamines?
No, you should not take more than one antihistamine at the same time unless advised by a doctor or pharmacist.
Can I drink alcohol while taking fexofenadine?
Alcohol may increase side effects such as drowsiness, so it is best to drink only small amounts.
Can fexofenadine be taken during pregnancy or breastfeeding?
Fexofenadine should only be taken during pregnancy or breastfeeding if recommended by a doctor. Alternative antihistamines may be advised first.
Important information about all medicines
Back to contentsImportant information about all medicines
Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.
This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
If you have any questions about this medicine ask your pharmacist.
Report side effects to a medicine or vaccine
If you experience side effects, you can report them online through the Yellow Card website.

Unsure about mixing medicines?
Check for possible interactions between medicines, supplements and foods before taking them together.
Frequently asked questions
How long does fexofenadine take to work?
Fexofenadine usually starts to work within 1 hour, with the full effect often felt after 2–3 hours.
How long does fexofenadine stay in your system?
Fexofenadine can remain in the body for around 24 hours, which is why it is usually taken once daily.
Can I take fexofenadine every day?
Yes, many people take fexofenadine daily during allergy seasons or for hives (chronic urticaria), but follow the advice of your doctor or pharmacist.
Can I take fexofenadine with other antihistamines?
No, you should not take more than one antihistamine at the same time unless advised by a doctor or pharmacist.
Can I drink alcohol while taking fexofenadine?
Alcohol may increase side effects such as drowsiness, so it is best to drink only small amounts.
Can fexofenadine be taken during pregnancy or breastfeeding?
Fexofenadine should only be taken during pregnancy or breastfeeding if recommended by a doctor. Alternative antihistamines may be advised first.
Further reading and references
- Manufacturer's PIL, Telfast® 120 mg Film-coated tablets, Sanofi, The electronic Medicines Compendium. Dated August 2022.
- Manufacturer's PIL, Telfast® 180 mg Film-coated tablets, Sanofi, The electronic Medicines Compendium. Dated August 2022.
- Manufacturer's PIL, Telfast® 30 mg tablets, Sanofi, The electronic Medicines Compendium. Dated November 2022.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewerView full bio

Dr Colin Tidy, MRCGP
General Practitioner, Medical Author
MBBS, MRCGP, MRCP (Paediatrics), DCH
Dr Colin Tidy is an NHS Doctor, based in Oxfordshire.
Article history
The information on this page is written and peer reviewed by qualified clinicians.
Next review due: 18 Dec 2027
19 Jun 2023 | Latest version

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