Tranexamic acid for bleeding
Cyklokapron
Peer reviewed by Sid DajaniLast updated by Michael Stewart, MRPharmSLast updated 9 Jun 2024
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Tranexamic acid is used to control unwanted bleeding. It reduces the amount of blood loss.
Side-effects are rare and usually minor. However, if you notice any changes to your vision you should let your doctor know about this as soon as possible.
At a glance
Tranexamic acid is a medicine used to stop or reduce heavy bleeding.
It works by preventing blood clots from breaking down.
Your doctor will tell you how many tablets to take each day.
It is important to tell your doctor about any existing medical conditions or other medicines you are taking.
Possible side-effects include feeling sick, diarrhoea, or eyesight problems.
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About tranexamic acid
Type of medicine | An antifibrinolytic medicine |
Used for | To prevent or treat heavy bleeding |
Also called | Cyklokapron® |
Available as | Tablets and injection |
Tranexamic acid is given to stop or reduce heavy bleeding. When you bleed, your body forms clots to stop the bleeding. In some people, these clots break down and the bleeding continues. Tranexamic acid works by stopping the clots from breaking down and so reduces the unwanted bleeding.
It is used to control bleeding in a number of different conditions. It reduces unwanted or heavy bleeding following some surgery (such as surgery on the prostate, bladder or cervix), nosebleeds, heavy periods (menorrhagia), bleeding inside the eye, tooth extraction in people who bleed more easily than normal, and in a condition called hereditary angio-oedema.
Tranexamic acid is available on prescription from a doctor and may be sold over-the-counter from pharmacies for the treatment of heavy periods.
Before taking tranexamic acid
Back to contentsSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking tranexamic acid it is important that your doctor knows:
If you are pregnant or breastfeeding.
If you have any problems with the way your kidneys work, or if you have blood in your urine.
If you have had a blood clot in an artery or vein.
If you have ever had a fit (convulsion).
If you have recently had a blood clotting problem called disseminated intravascular coagulation.
If you are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines. If you are taking the contraceptive pill, please make sure that your doctor is aware of this.
If you have ever had an allergic reaction to a medicine.
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How to take tranexamic acid
Back to contentsBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about tranexamic acid and will provide you with a full list of the side-effects which you may experience from taking it.
Take the tablets exactly as your doctor tells you to. Your doctor will tell you how many tablets to take each day and how long the course of treatment will last. Your dose will also be printed on the label of the pack to remind you about what the doctor said to you. It is usual to be asked to take 2-3 tablets, two or three times a day, but your dose may be different to this.
Swallow the tablets whole with a drink of water - do not crush or chew the tablets.
Tranexamic acid can be taken either before or after food.
If you forget to take a dose, do not worry, just leave out the missed dose and take the next dose when it is due. Do not take two doses together to make up for a forgotten dose.
Getting the most from your treatment
Back to contentsTry to keep any regular appointments with your doctor. This is so your doctor can check on your progress.
Tranexamic acid is usually taken for short periods of time only.
If you are having an operation or any dental treatment, remember to tell the person carrying out the treatment that you are taking tranexamic acid.
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Can tranexamic acid cause problems?
Back to contentsAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the side-effects associated with tranexamic acid, although these occur only rarely. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Speak with your doctor or pharmacist if any of the following become troublesome.
Tranexamic acid side-effects | What can I do if I experience this? |
Feeling sick (nausea) or being sick (vomiting) | Stick to simple meals - avoid rich and spicy food. If you are not already doing so, try taking the tablets after meals |
Diarrhoea | Drink plenty of water to replace the lost fluids |
Eyesight problems (such as problems with your colour vision) | Let your doctor know about this as soon as possible as your treatment will need to be reviewed |
If you experience any other symptoms which you think may be due to the medicine, speak with your doctor or pharmacist for further advice.
How to store tranexamic acid
Back to contentsKeep all medicines out of the reach and sight of children.
Store in a cool, dry place, away from direct heat and light.
Important information about all medicines
Back to contentsImportant information about all medicines
Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.
This medicine is for you. Do not give it to other people even if their condition appears to be the same as yours.
If you buy any medicines, check with a pharmacist that they are suitable to take with your other medicines.
Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
If you have any questions about this medicine ask your pharmacist.
Report side effects to a medicine or vaccine
If you experience side effects, you can report them online through the Yellow Card website.

Unsure about mixing medicines?
Check for possible interactions between medicines, supplements and foods before taking them together.
Frequently asked questions
How does tranexamic acid work to stop bleeding?
When you experience bleeding, your body typically forms clots to stop it. However, in some individuals, these clots can break down too quickly, leading to continued bleeding. Tranexamic acid works by preventing these clots from breaking down, which helps to reduce the unwanted bleeding.
Can I take tranexamic acid if I am already on other medication?
It is important to inform your doctor about all other medicines you are taking, including those bought without a prescription, herbal remedies, and complementary medicines. This is because some medicines may not be suitable to take with tranexamic acid, or may require extra care. Specifically, if you are taking the contraceptive pill, ensure your doctor is aware.
What should I do if I forget to take a dose of tranexamic acid?
If you miss a dose, you should not worry. Simply leave out the missed dose and take your next dose when it is due. Do not take two doses together to try and make up for the one you forgot.
Are there any specific foods or drinks I should avoid while taking tranexamic acid?
The article states that tranexamic acid can be taken either before or after food. If you experience feeling sick or being sick, it suggests sticking to simple meals and avoiding rich or spicy food, and trying to take the tablets after meals if you're not already doing so. There are no other specific dietary restrictions mentioned.
How long will I typically need to take tranexamic acid?
Tranexamic acid is usually taken for short periods of time only. Your doctor will provide specific instructions on how long your course of treatment should last.
What should I do if I experience side-effects like feeling sick or diarrhoea?
If you experience feeling sick (nausea) or being sick (vomiting), try to stick to simple meals and avoid rich and spicy food. You could also try taking the tablets after meals. For diarrhoea, drink plenty of water to replace any lost fluids. If these or any other side-effects become troublesome, you should speak with your doctor or pharmacist for advice.
Can I get tranexamic acid without a prescription?
Tranexamic acid is available on prescription from a doctor. However, for the treatment of heavy periods, it may also be sold over-the-counter from pharmacies.
Further reading and references
- Manufacturer's PIL, Cyklokapron® 500 mg film-coated Tablets; Mylan (Viatris), The electronic Medicines Compendium. Dated February 2024.
- Medicines Complete BNF 89th Edition; British Medical Association and Royal Pharmaceutical Society of Great Britain, London.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Article history
The information on this page is written and peer reviewed by qualified clinicians.
Next review due: 22 May 2027
9 Jun 2024 | Latest version

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