Sepsis warning signs you need to know
Peer reviewed by Dr Krishna Vakharia, MRCGPLast updated by Amberley DavisLast updated 11 Sept 2023
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Sepsis is a reaction by the body to severe infection with a bacterial, viral or fungal germ. It's always a medical emergency, and can be fatal if not caught early. You can arm yourself against this by knowing the symptoms so you can seek help early.
In this article:
Sepsis is a fairly new word, but it certainly isn't a new problem. Septicaemia, sometimes known as blood poisoning, happens when an infection spreads through your bloodstream. Sepsis is an infection affecting the whole body, and strictly speaking refers to the way your body responds to this infection.
Around 1 in 500 people develop sepsis in the UK every year. It's more likely if your immune system isn't as strong as it should be. This means children (whose immune system is still developing) and over-75s (your immune system wanes with age) are at high risk. Your risks are also raised if you're on steroids or cancer treatment, have a medical condition like blood cancer, have had surgery or drink a lot of alcohol, have a long-term catheter, or have diabetes.
Sepsis warning signs
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The signs to look for
The Sepsis Trust, which campaigns to raise awareness of sepsis, has developed a checklist to help you spot signs of possible sepsis:
Slurred speech or confusion.
Extreme shivering or muscle pain.
Passing no urine (in a day).
Severe breathlessness or sleepiness.
It feels like you're going to die or pass out.
Skin mottled or discoloured.
An extremely high or a very low temperature, repeated vomiting, seizures, and a rash which doesn't fade when you press a glass against it are also possible warning signs.
In children, the signs may be different. You should think sepsis if a child:
Is breathing very fast.
Is confused or disorientated.
Has a fit or convulsion.
Has clammy, cold skin and looks blue, pale or patchy (mottled).
Has a rash that does not fade when you press it.
Is very lethargic or difficult to wake.
Feels abnormally cold to touch.
In children under five years, not feeding, repeated vomiting or no wet nappies for 12 hours are also concerning. If you notice any of these symptoms, don't delay - early treatment saves lives.
Patient picks for Meningitis and sepsis
Infections
Meningitis symptoms checklist
The following are possible symptoms of meningitis or septicaemia. But note: not all symptoms may be present. For example, the classic symptoms of neck stiffness and rash may not occur. See below for other possible symptoms. If you suspect meningitis or septicaemia - get medical help immediately.
by Dr Mary Harding, MRCGP
Infections
Adult sepsis safety net
Sepsis is a severe condition that can be fatal if not caught early. Signs and symptoms can be vague or severe. This leaflet will let you know what symptoms to look out for.
by Dr Krishna Vakharia, MRCGP
Early diagnosis saves lives
If a doctor suspects sepsis, you'll be admitted to hospital immediately. Treatment depends partly on the cause - for instance, bacterial infections will be treated with antibiotics given through a drip into your bloodstream, and you may need surgery to remove collections of pus which have built up.
In the meantime, you'll have supportive treatment to help your body keep going:
Fluid through a drip.
Oxygen through a mask.
Possible admission to an intensive care unit for breathing and other support.
Without early diagnosis, between 1 and 5 in 10 people with sepsis won't survive. But with early treatment, the outlook is much better. It can be a long road to recovery, though. Sepsis affects your whole body, and can stop your kidneys and liver from functioning properly or your blood from clotting. You're likely to be in hospital for several weeks, and may need support at home for several months.
A condition called post-sepsis syndrome can leave you feeling tired, weak and short of breath. You may be off your food, prone to frequent infections and suffer from joint and chest pains. In addition, sepsis can take its toll mentally, leaving you depressed and anxious.
That means you'll need support and understanding from your loved ones. Don't expect to bounce back to health - instead take things gently, increasing your levels of activity very slowly. If you're struggling with day-to-day activities like shopping, cooking or cleaning, your local social services department can help with services like home help and meals at home (meals on wheels).
With thanks to My Weekly where this was originally published.
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Article history
The information on this page is peer reviewed by qualified clinicians.
Next review due: 11 Sept 2026
11 Sept 2023 | Latest version
29 Nov 2018 | Originally published
Authored by:
Dr Sarah Jarvis MBE, FRCGP
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