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Can I take Atorvastatin and Cordyceps together?

Drug interaction guide

Taking cordyceps with atorvastatin might increase the risk of muscle-related side effects. There is also a theoretical risk that cordyceps could affect how your liver processes the statin, or it could have an additive effect on lowering your cholesterol.

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Why this happens

Both atorvastatin and cordyceps can affect liver enzymes (specifically CYP3A4). If cordyceps slows down the breakdown of atorvastatin, the levels of the medicine in your blood could rise, increasing the risk of muscle pain or damage (myopathy). Additionally, because cordyceps may have its own cholesterol-lowering properties, taking both together might lower your cholesterol more than intended.

What you should do

Speak to your doctor or pharmacist before combining these two. If you decide to take them together, be very alert for any unexplained muscle pain, tenderness, or weakness, and report these symptoms to your GP immediately.

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Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 24 Jan 2026 | Originally published
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