Can I take Cordyceps and Reishi together?
Drug interaction guide
Originally published 24 Jan 2026
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Taking cordyceps and reishi together may increase the risk of bruising or bleeding. Both supplements can also lower blood sugar levels, which might lead to symptoms of low blood sugar (hypoglycaemia) such as dizziness or shakiness.
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Why this happens
Both cordyceps and reishi have 'antiplatelet' effects, meaning they make the blood less likely to clot. When used together, this effect is additive. Additionally, both fungi can mimic or enhance the effects of insulin, leading to a combined lowering of blood glucose.
What you should do
It is generally safe for healthy individuals to take these together in moderate amounts, but you should monitor for signs of easy bruising or bleeding gums. If you are scheduled for surgery, stop taking both at least two weeks beforehand. If you have diabetes or take blood-thinning medication (like warfarin or aspirin), consult your doctor before combining these supplements.
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Using other medicines?
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
24 Jan 2026 | Originally published

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