Can I take Iron and Vitamin c together?
Drug interaction guide
Originally published 24 Jan 2026
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Taking Vitamin C alongside iron supplements can increase the amount of iron your body absorbs into the bloodstream. While this is often beneficial for treating iron-deficiency anaemia, it may increase the risk of stomach-related side effects like nausea or constipation.
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Why this happens
Vitamin C (ascorbic acid) changes the chemical form of iron in the stomach to a version that is more easily dissolved and absorbed by the gut lining. It also helps prevent iron from binding to other substances in your food that might block its absorption.
What you should do
It is generally recommended to take iron with a source of Vitamin C (like a glass of orange juice) to help it work better. However, if you find this causes stomach upset, you can take them separately or with a small amount of food. If you have a condition that causes iron overload (like haemochromatosis), speak to your doctor before combining them.
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Important precautions
Iron overdose in children
Keep iron supplements strictly out of reach of children. Even a small accidental overdose can be fatal for a child.
Tetracycline or Quinolone antibiotic use
Do not take iron at the same time as antibiotics. Iron stops these medicines from working; space them at least 2 hours apart.
Food and drink warnings
Tea, Coffee, and Caffeinated drinks
Caffeine and compounds called tannins found in tea and coffee significantly reduce the amount of iron your body can absorb. Avoid these drinks for at least one hour before and two hours after taking your iron supplement.
Dairy products (Milk, Cheese, Yoghurt)
Calcium in dairy products prevents iron from being absorbed properly. Do not take your iron supplement at the same time as eating or drinking dairy. Leave a gap of at least two hours.
Eggs and Whole-grain Cereals
These contain compounds (phytates and phosphates) that can bind to iron and stop it from being absorbed. It is best to take iron on an empty stomach, but if it upsets your stomach, avoid taking it with these specific foods.
Vitamin C (Orange juice, Citrus fruits)
This is a positive interaction. Taking iron with a glass of orange juice or foods high in Vitamin C actually helps your body absorb the iron more effectively.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
24 Jan 2026 | Originally published

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