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Can I take Turkey tail and White button together?

Drug interaction guide

There are no known negative interactions between Turkey Tail (Trametes versicolor) and White Button mushrooms (Agaricus bisporus). Both are edible fungi that are often consumed together in dietary supplements or meals.

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Why this happens

Both mushrooms contain bioactive compounds called polysaccharides (such as beta-glucans). Rather than interfering with each other, they may have a complementary effect on the immune system without affecting how the body absorbs or processes either mushroom.

What you should do

It is generally safe to consume these together. However, as with any supplement, start with small amounts to ensure you do not have an individual sensitivity or digestive upset. If you are taking immunosuppressant medication or have an autoimmune condition, consult your doctor before using medicinal mushroom supplements.

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Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 24 Jan 2026 | Originally published
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