Erythema Toxicum Neonatorum Baby Acne

Last updated by Peer reviewed by Dr Doug McKechnie
Last updated Meets Patient’s editorial guidelines

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Erythema toxicum neonatorum (ETN) is a common skin rash affecting healthy newborn babies. It is not serious, does not cause the baby any harm and clears up without any treatment. It is sometimes known as erythema toxicum, baby acne or toxic erythema of the newborn.

Baby acne is small, inflamed bumps that can appear on a baby's neck, face, back and chest shortly after birth. The name erythema toxicum neonatorum is confusing because the condition is not toxic. It is also not the same as the acne that affects young people and adults.


Erythema is the medical word for redness. Neonatorum refers to the fact that the rash occurs in the neonatal period. The neonatal period is the time between birth and 28 days after birth. A baby in this age range is called a neonate.

Erythema toxicum neonatorum: baby acne

Baby acne
Own image [selbst erstellt] (Fragegeist), Public domain, via Wikimedia Commons

By Fragegeist - selbst erstellt (own self-made image), Public domain, via Wikimedia Commons

The rash of ETN generally looks like red blotches, mainly affecting the face and body (trunk). It does occur on the arms and legs too (but is rare on the palms and soles of the feet). Characteristics of baby acne include:

  • Little, raised spots called papules are common.
  • Little pus-filled spots (pustules) or fluid-filled small blisters (vesicles).
  • There may be many spots or very few.
  • The different spots vary in size.
  • The spots blanch with light pressure (this means that they become pale and fade when pressed).
  • The rash can be temporary (very transient) and sometimes individual spots can disappear within hours while new ones will appear somewhere else.

The baby appears well and the rash does not seem to cause any bother.

Note: if there is any doubt as to the cause of a skin rash in any baby or child, it is essential that you seek medical advice and a firm diagnosis for any other potential skin conditions. This is especially important if your baby seems unwell in any way. For example, if your baby has a temperature (fever), is not feeding, is lacking in energy (lethargic) or is inconsolable and not the same as normal. Other rashes can occur in babies and may be the sign of serious illness.

The exact cause is unknown. It is not due to an infection, even though pus-filled spots (pustules) are often present.

Various ideas have been suggested, including the possibility that it is a normal effect of a baby's immune system reacting to the first microbes from the skin travelling down the hair follicles. It is not thought to be an allergic problem. It is also not related to whether the baby is breast-fed or bottle-fed.

Erythema toxicum neonatorum is a very common rash. Up to 4 or 5 in every 10 babies develop baby acne. It seems to be more common in full term newborn babies(between 37 and 40 weeks of gestation) compared with premature babies.

On average, baby acne occurs in healthy babies born at full term, between 3 and 14 days of life. The rash can occur in the first 48 hours of life but 9 out of 10 cases are in babies more than 2 days old.

Overall, it seems to be more common in babies who are heavier at birth, in babies born in the summer or autumn and in babies who are fed milk powder substitute or a mixed diet.

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Usually, no tests are needed to diagnose baby acne. The rash is generally easily recognisable by doctors and midwives. Tests may be needed if there is any uncertainty as to the cause of the rash, particularly if your baby is unwell.

There is no specific treatment needed for baby acne. The rash settles completely without any treatment.

If your baby develops erythema toxicum neonatorum, there is no need to worry. Your baby will not be in any discomfort or have any distress related to the rash. The skin may look red and angry (and your baby may look less than perfect temporarily) but do your best to ignore it.

Avoid over-washing the baby - babies have delicate skin that can dry out easily with detergents (soaps) so continue to wash as normal using warm water. Resist any temptation to pick, squeeze or burst any pus-filled spots (pustules). This would make a skin infection more likely to occur and may lead to scarring.

Creams and lotions are not required for the rash. If you are already using products to moisturise and wash your baby it is fine to continue them but ensure they are fragrance-free and designed for use in babies.

Typically, baby acne lasts for a few days only. In almost all cases it has completely gone within two weeks of life. Very occasionally the rash can return (recur). This can happen up to 6 weeks of age. Usually recurrences are mild.

There are no long-term problems associated with ETN. The rash settles spontaneously, leaving normal skin. Of course, some babies develop dry skin, eczema or other skin problems but these are not related to ETN.

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Further reading and references

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