Can I take 10 and Valsartan together?
Drug interaction guide
Originally published 14 Mar 2026
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Taking ibuprofen (Nurofen) with valsartan can make your blood pressure medicine less effective. More importantly, it can significantly increase the risk of kidney problems, especially if you are older, dehydrated, or already have kidney issues. It can also cause your body to hold onto too much potassium, which can be dangerous for your heart.
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Why this happens
Valsartan works by relaxing blood vessels and helping the kidneys remove salt and water. Ibuprofen blocks chemicals called prostaglandins that help keep the blood vessels in the kidneys open. When both are taken together, the blood flow to the kidneys can drop too low, and the blood pressure-lowering effect of valsartan is reduced.
What you should do
Back to contentsYou should avoid taking ibuprofen while on valsartan unless your doctor specifically tells you to. If you need pain relief, paracetamol is usually a safer choice, but you should still limit your alcohol intake when taking it. If you have already taken both, watch for signs of kidney trouble like swollen ankles or changes in how much you urinate, and contact your doctor.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published
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