Can I take 15 and 20ug h transdermal together?
Drug interaction guide
Originally published 14 Mar 2026
Meets Patient’s editorial guidelines
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You are asking about using two patches of the same medication (buprenorphine) at the same time. This is effectively a double dose, which significantly increases the risk of dangerous side effects such as severe drowsiness, breathing difficulties, and accidental overdose.
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Why this happens
Both patches contain the same active ingredient (buprenorphine), which is an opioid painkiller. Using a 15 microgram/hour patch and a 20 microgram/hour patch together creates a total dose of 35 micrograms/hour. This may be higher than the dose your doctor intended for you.
What you should do
Back to contentsDo not apply both patches at once unless specifically instructed to do so by your doctor or pain specialist. If you have already applied both and feel unusually sleepy, dizzy, or have trouble breathing, remove the patches immediately and seek emergency medical help. Always follow the specific dosage prescribed on your dispensing label.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Taking fluoxetine with Abilify (aripiprazole) can significantly increase the amount of Abilify in your bloodstream. This makes you much more likely to experience side effects such as extreme sleepiness, restlessness (feeling like you cannot sit still), uncontrollable body movements (tremors or twitching), and dizziness. There is also a small but serious risk of a heart rhythm problem called QT prolongation.

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Can I take Amlodipine and Omemprazole together?
There is no significant interaction between amlodipine and omeprazole. It is generally safe to take these two medicines together.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published

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