Can I take 4.5mg and Lantus for in a cartridge together?
Drug interaction guide
Originally published 14 Mar 2026
Meets Patient’s editorial guidelines
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Low-dose naltrexone (LDN) may occasionally cause changes in blood sugar levels or alter how your body responds to insulin. While not a common interaction, some patients using both may experience unexpected drops in blood sugar (hypoglycaemia).
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Why this happens
Naltrexone can influence the endocrine system and metabolic processes. In some cases, it may increase insulin sensitivity, meaning your usual dose of Lantus (insulin glargine) could work more strongly than expected.
What you should do
Back to contentsYou should monitor your blood sugar levels more frequently when starting or changing the dose of naltrexone. If you notice your blood sugar is consistently lower than usual, or if you experience symptoms of a 'hypo' (such as shakiness, sweating, or confusion), contact your doctor or diabetes specialist. They may need to adjust your Lantus dose.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published
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