Can I take 50 and Probiotics together?
Drug interaction guide
Originally published 14 Mar 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
- Audio Version
There is no known interaction between 50mg of a medication (assuming a standard dose of a common medicine) and probiotics. However, if the '50' refers to an antibiotic, the antibiotic may kill the 'friendly' bacteria in the probiotic, making the supplement less effective.
In this article:
Video picks for Drug interactions
Continue reading below
Why this happens
Probiotics contain live beneficial bacteria. Antibiotics are designed to kill bacteria. If taken at the same time, the antibiotic cannot distinguish between 'bad' infection-causing bacteria and the 'good' bacteria in the probiotic, leading to the destruction of the probiotic organisms.
What you should do
Back to contentsIt is generally safe to take probiotics with most medications. If you are taking an antibiotic, it is best to space the doses at least 2 to 3 hours apart to ensure the probiotic remains effective. If '50' refers to a different type of medication, please specify the drug name for a more accurate assessment.
Continue reading below
Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Treatment and medication
Can I take Allerwel am and Calpol together?
There are no known harmful interactions between Allerwel AM and Calpol. It is generally safe to take these two medicines together as long as you follow the recommended doses for each.

Treatment and medication
Can I take Alodipine and Bisoprolol together?
Taking amlodipine and bisoprolol together can cause your blood pressure to drop lower than if you took either medicine alone. It can also significantly slow down your heart rate. This may make you feel dizzy, lightheaded, faint, or unusually tired.
Continue reading below
Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.