Can I take 50 and Probiotics together?
Drug interaction guide
Originally published 12 May 2026
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There is no known interaction between 50mg of a medication (assuming a standard dose of a common medicine) and probiotics. However, if the '50' refers to an antibiotic, the antibiotic may kill the 'friendly' bacteria in the probiotic, making the supplement less effective.
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Why this happens
Probiotics contain live beneficial bacteria. Antibiotics are designed to kill bacteria. If taken at the same time, the antibiotic cannot distinguish between 'bad' infection-causing bacteria and the 'good' bacteria in the probiotic, leading to the destruction of the probiotic organisms.
What you should do
Back to contentsIt is generally safe to take probiotics with most medications. If you are taking an antibiotic, it is best to space the doses at least 2 to 3 hours apart to ensure the probiotic remains effective. If '50' refers to a different type of medication, please specify the drug name for a more accurate assessment.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
12 May 2026 | Originally published
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