Can I take 50 and Sertraline together?

Why this happens

Both 5-HTP and sertraline increase the levels of serotonin in the brain. Sertraline (an SSRI antidepressant) stops the brain from reabsorbing serotonin, while 5-HTP is a building block that the body uses to make more serotonin. Using them at the same time creates a 'double hit' effect that can overwhelm the nervous system.

Do not take 5-HTP if you are taking sertraline. If you have already taken both and feel unwell, seek medical help immediately. Always talk to your doctor or pharmacist before starting any herbal supplements or vitamins while on prescription medication.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.