Can I take Aciclovir and Ibrutinib together?

Why this happens

Both aciclovir and ibrutinib are processed and removed from the body by the same transport system in the kidneys (specifically a protein called MATE1). Because they are 'competing' for the same exit route, ibrutinib can slow down the removal of aciclovir, leading to higher levels of the antiviral medicine in your system.

You can usually take these medicines together, but you should be monitored for side effects. It is important to stay well-hydrated by drinking plenty of water to help protect your kidneys. If you notice any changes in how much you urinate, or if you experience unusual tiredness or skin rashes, contact your doctor. Your doctor may decide to adjust your aciclovir dose if you have existing kidney problems.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.