Can I take Adizem and Baclofen together?
Drug interaction guide
Originally published 14 Mar 2026
Meets Patient’s editorial guidelines
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Taking Adizem (diltiazem) and baclofen together can cause your blood pressure to drop lower than intended. This may make you feel dizzy, lightheaded, or faint, especially when standing up quickly. It may also increase the muscle-relaxing effects of baclofen.
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Why this happens
Both medications can lower blood pressure. Adizem is a calcium channel blocker designed to lower blood pressure and treat heart conditions, while baclofen (a muscle relaxant) has a known side effect of lowering blood pressure. When used together, these effects add up (an additive effect).
What you should do
Back to contentsYou should use this combination with caution. Monitor your blood pressure regularly at home if possible. To prevent dizziness, try to get up slowly from a sitting or lying position. If you feel very dizzy, faint, or unusually tired, contact your doctor, as they may need to adjust your dosages.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published
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