Can I take Alcohol and Citalopram together?

It is best to avoid alcohol, especially when you first start taking citalopram or if your dose has recently increased as both alcohol and citalopram affect the central nervous system (the brain).

When used together, they have an 'additive effect,' meaning they combine to increase the sedative (calming/sleepy) impact on the brain. While alcohol does not significantly change the levels of citalopram in your blood, it changes how your brain responds to the drug.

It is best to avoid or strictly limit alcohol while taking citalopram. If you do choose to drink, keep it to a very small amount and do not drive or operate machinery, as your reactions will be much slower. Be aware that it is illegal to drive if your driving is impaired by any substance, including a combination of prescription medicine and alcohol.

Important precautions

Depression and anxiety disorders

You may experience an increase in suicidal thoughts or the urge to self-harm when first starting this medicine or changing the dose. This is more common in young adults under 25. Contact your doctor or go to hospital immediately if this happens.

Heart rhythm disorders (Long QT syndrome)

Citalopram can affect your heart rhythm. You must not take it if you have a known heart rhythm problem or are taking other medicines that affect the heart's electrical cycle.

Bleeding disorders

Citalopram increases your risk of bleeding, particularly in the stomach. Use with caution if you take blood-thinning medicines (like warfarin) or anti-inflammatory painkillers (like ibuprofen or aspirin).

Serotonin Syndrome

Taking citalopram with other medicines that increase serotonin (such as St John’s Wort, tramadol, or other antidepressants) can cause a life-threatening condition called serotonin syndrome. Symptoms include high fever, agitation, confusion, and muscle twitching.

Low sodium levels (Hyponatraemia)

Citalopram can cause a serious drop in blood sodium levels, especially in the elderly. Seek medical help if you experience extreme tiredness, confusion, or muscle twitching.

Caffeine (Coffee, Tea, Energy Drinks)

Citalopram can sometimes cause feelings of restlessness or jitteriness, especially when you first start taking it. Caffeine is a stimulant that can worsen these side effects and may increase feelings of anxiety. It is advisable to monitor your caffeine intake.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.