Can I take Allegra and Claribid together?

Why this happens

Clarithromycin (Claribid) blocks a specific protein in the body called P-glycoprotein. This protein is responsible for pumping fexofenadine (Allegra) out of the body. When this protein is blocked, more fexofenadine stays in your system.

You can take these medicines together, but you should be aware of increased side effects. If you feel unusually sleepy or dizzy, contact your doctor. No specific dose adjustment is usually needed, but caution is advised.

Heart Rhythm Disorders (Long QT Syndrome)

Do not take this medicine if you have a history of heart rhythm problems or 'long QT syndrome', as it can trigger life-threatening heart disturbances. Check with your pharmacist if you take other medicines for your heart or blood pressure.

Statin Medication Use (e.g., Simvastatin, Atorvastatin)

Do not take this medicine if you are taking certain statins (cholesterol-lowering drugs) like simvastatin or atorvastatin. Combining them can cause severe muscle breakdown and kidney damage.

Indigestion Remedies (Antacids)

Do not take indigestion remedies (antacids containing aluminium or magnesium) within 2 hours of taking this medicine, as they will stop the allergy relief from working properly.

Fruit juices (Grapefruit, Orange, Apple)

Do not drink fruit juices (especially grapefruit, orange, or apple juice) within 2 hours of taking this medicine. These juices can significantly reduce the amount of medicine absorbed by your body, making it less effective.

Alcohol

While there is no direct interaction between clarithromycin and alcohol, it is best to avoid drinking alcohol while you have an infection. Alcohol can worsen side effects like dizziness or stomach upset and may slow down your recovery.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.