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Can I take Alodipine and Bisoprolol together?

Drug interaction guide

Taking amlodipine and bisoprolol together can cause your blood pressure to drop lower than if you took either medicine alone. It can also significantly slow down your heart rate. This may make you feel dizzy, lightheaded, faint, or unusually tired.

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Why this happens

Both medicines work to lower blood pressure but in different ways. Amlodipine relaxes your blood vessels, while bisoprolol slows your heart rate and reduces the force of your heart's contractions. When used together, these effects add up (an additive effect).

This is a very common combination used to treat high blood pressure or heart conditions, but it requires careful monitoring. When you first start taking them together, or if your dose is increased, be careful when standing up quickly. Monitor your blood pressure and heart rate at home if advised by your doctor. If you feel very dizzy, faint, or notice a very slow pulse, contact your GP.

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Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 14 Mar 2026 | Originally published
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