Can I take Allopurinol bp and Rosuvastatin together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
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There is no known direct interaction between allopurinol and rosuvastatin. Both medications are generally safe to take together. However, both drugs can rarely affect the liver or cause muscle-related side effects, so it is important to be aware of any new symptoms.
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Why this happens
Allopurinol (used for gout) and rosuvastatin (a statin for cholesterol) are processed by different pathways in the body. Allopurinol is primarily cleared by the kidneys, while rosuvastatin is processed by the liver and excreted through bile. Because they do not compete for the same enzymes or transport systems, they do not interfere with each other's levels in the blood.
What you should do
You can continue taking both medications as prescribed. As with any statin, you should contact your doctor if you experience unexplained muscle pain, tenderness, or weakness. It is also standard practice for your doctor to monitor your liver function through routine blood tests while you are on these medications.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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