Skip to main content

Can I take Allopurinol bp and Rosuvastatin together?

Drug interaction guide

There is no known direct interaction between allopurinol and rosuvastatin. Both medications are generally safe to take together. However, both drugs can rarely affect the liver or cause muscle-related side effects, so it is important to be aware of any new symptoms.

Continue reading below

Why this happens

Allopurinol (used for gout) and rosuvastatin (a statin for cholesterol) are processed by different pathways in the body. Allopurinol is primarily cleared by the kidneys, while rosuvastatin is processed by the liver and excreted through bile. Because they do not compete for the same enzymes or transport systems, they do not interfere with each other's levels in the blood.

What you should do

You can continue taking both medications as prescribed. As with any statin, you should contact your doctor if you experience unexplained muscle pain, tenderness, or weakness. It is also standard practice for your doctor to monitor your liver function through routine blood tests while you are on these medications.

Continue reading below

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

Continue reading below

Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 25 Jan 2026 | Originally published
flu eligibility checker

Ask, share, connect.

Browse discussions, ask questions, and share experiences across hundreds of health topics.

symptom checker

Feeling unwell?

Assess your symptoms online for free

Sign up to the Patient newsletter

Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.

Please enter a valid email address

By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.