Can I take Alodipine and Bendroflaumazide together?
Drug interaction guide
Originally published 12 May 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
- Audio Version
Taking these two medicines together can cause your blood pressure to drop lower than if you took either one alone. While this is often the goal of treatment, it can sometimes make you feel dizzy, lightheaded, or faint, especially when you stand up quickly.
In this article:
Video picks for Drug interactions
Continue reading below
Why this happens
Both medicines work to lower blood pressure but in different ways: amlodipine relaxes your blood vessels, while bendroflumethiazide helps your body remove excess salt and water. Combining them has an 'additive' effect, meaning their blood-pressure-lowering powers are added together.
What you should do
Back to contentsIt is very common for doctors to prescribe these together. When you first start the combination, take extra care when standing up from a sitting or lying position. If you feel very dizzy, have a persistent headache, or feel like you might faint, contact your GP. They may want to monitor your blood pressure or check your kidney function and salt levels with a blood test.
Continue reading below
Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Drug interactions checker
Can I take Sertraline and Fluoxetine together?
Taking sertraline and fluoxetine together significantly increases the risk of a rare but serious condition called serotonin syndrome. This happens because both medicines work by increasing the level of a chemical called serotonin in your brain. If levels get too high, it can cause symptoms like shivering, diarrhoea, confusion, severe muscle tightness, fever, and even seizures. Additionally, fluoxetine can slow down how your body breaks down sertraline, leading to a build-up of the drug in your system and increasing the risk of side effects.

Drug interactions checker
Can I take Calcium and Esomeprazole together?
Taking esomeprazole for a long time may reduce how much calcium your body absorbs from your diet or from certain supplements. This can lead to weaker bones and an increased risk of fractures, particularly in the hip, wrist, or spine, if used at high doses for over a year.
Continue reading below
Article history
The information on this page is written and peer reviewed by qualified clinicians.
12 May 2026 | Originally published

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.