Can I take Alogliptin and Atorvastatin together?

Why this happens

Alogliptin and atorvastatin are processed by different pathways in the body. Alogliptin is primarily removed by the kidneys, while atorvastatin is broken down by specific enzymes in the liver (CYP3A4). Because they do not compete for the same 'processing machinery,' they do not interfere with each other's levels in the blood.

What you should do

You can continue to take both medications as prescribed by your doctor. As with any medication for diabetes and cholesterol, you should continue to monitor your blood sugar levels regularly and report any unusual muscle pain or weakness to your healthcare provider.

Important precautions

Pregnancy

You must not take atorvastatin if you are pregnant or planning to become pregnant, as it can harm the developing baby. Use effective contraception while taking it.

Muscle disorders - atorvastatin

Seek immediate medical advice if you experience unexplained muscle pain, tenderness, or weakness. In rare cases, this can lead to serious kidney problems.

Pancreatitis

Stop taking alogliptin and contact a doctor immediately if you experience severe and persistent stomach pain, which may reach through to your back, as this can be a sign of an inflamed pancreas.

Food and drink warnings

Grapefruit juice

Grapefruit juice can increase the level of atorvastatin in your blood, which may increase the risk of side effects like muscle pain or damage. Avoid drinking large amounts (more than 1.2 litres daily), but a small glass is usually safe.

Alcohol

Drinking large amounts of alcohol while taking atorvastatin can increase your risk of liver problems. It is best to keep your intake within the recommended limits (no more than 14 units per week).

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.