Can I take Amitriptyline and Ripinrole together?

Why this happens

Both medications affect chemicals in the brain and have 'sedating' effects that add together. Amitriptyline can also interfere with how the liver processes ropinirole, potentially leading to higher levels of the drug in your system. Additionally, both drugs can lower blood pressure, increasing the risk of falls.

What you should do

Speak to your doctor before taking these together. If your doctor prescribes both, be very careful when performing tasks that require alertness, such as driving. Move slowly when standing up from a sitting or lying position. Seek medical help immediately if you experience high fever, muscle stiffness, or agitation.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.