Can I take Amitriptyline and Vitamin a together?
Drug interaction guide
Originally published 14 Mar 2026
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There is no known direct interaction between amitriptyline and Vitamin A supplements when taken at standard recommended doses.
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Why this happens
Amitriptyline is an antidepressant processed by the liver, while Vitamin A is a fat-soluble vitamin. They do not share the same metabolic pathways or interfere with each other's effects in the body.
What you should do
Back to contentsYou can safely take these together. However, always stick to the recommended daily allowance for Vitamin A, as excessive amounts (hypervitaminosis A) can cause side effects like headaches or dizziness, which could be confused with the side effects of amitriptyline.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published

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