Can I take Amlodipine besilate and Binosto together?
Drug interaction guide
Originally published 14 Mar 2026
Meets Patient’s editorial guidelines
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There is no direct interaction between amlodipine and Binosto (alendronic acid). However, Binosto must be taken in a very specific way to ensure it is absorbed properly and does not irritate your food pipe (oesophagus). Taking other medicines, including amlodipine, at the same time as Binosto can stop the Binosto from working.
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Why this happens
Amlodipine is a blood pressure medication, and Binosto is a bisphosphonate for bone strength. They do not interfere with each other's chemistry in the body. However, Binosto is very sensitive to anything else in the stomach; other medicines, food, or drinks can prevent it from being absorbed into your bloodstream.
What you should do
Back to contentsYou can safely take both medications, but you must space them out. Take your Binosto first thing in the morning on an empty stomach with a full glass of plain water. Wait at least 30 minutes before taking your amlodipine, eating any food, or drinking other liquids. Do not lie down for at least 30 minutes after taking Binosto to prevent irritation to your throat.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published
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