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Can I take Amlodopine and Citalopram together?

Drug interaction guide

Taking amlodipine and citalopram together may increase the risk of developing an abnormal heart rhythm. While both are commonly prescribed together, they can both affect the electrical activity of your heart. In rare cases, this can lead to a serious condition called QT prolongation, where the heart muscle takes longer than normal to recharge between beats. This can cause palpitations, dizziness, or fainting.

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Why this happens

Both medications have the potential to affect the 'QT interval' (the electrical timing of the heart). Citalopram is known to cause this effect, especially at higher doses, and amlodipine may occasionally contribute to this or change how the heart responds to electrical signals.

What you should do

For most people, this combination is safe, but you should use caution. Ensure your doctor knows you are taking both. Seek medical help immediately if you feel a sudden fast or pounding heartbeat, severe dizziness, or if you faint. Your doctor may occasionally want to check your heart rhythm with an ECG (heart trace) or monitor your salt levels (electrolytes) through blood tests.

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Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 25 Jan 2026 | Originally published
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