Can I take Ashwagandha and Oestrogel pump-pack together?

You should consult your doctor or a pharmacist before combining ashwagandha with Oestrogel as ashwagandha may increase the levels of oestrogen in your body.

Why this happens

Ashwagandha is thought to have 'pro-oestrogenic' properties, meaning it may stimulate oestrogen receptors or increase the production of precursors to oestrogen.

When used with Hormone Replacement Therapy (HRT) like Oestrogel, this could lead to an additive effect, resulting in higher-than-normal oestrogen activity.

What you should do

If you decide to use both, monitor yourself closely for signs of too much oestrogen, such as breast tenderness, bloating, headaches, or mood swings. Your doctor may need to monitor your hormone levels more frequently.

Important precautions

Hyperthyroidism (overactive thyroid)

Ashwagandha can increase thyroid hormone levels, which may worsen hyperthyroidism or interfere with thyroid medication.

History of blood clots or breast cancer

Oestrogel must not be used if you have ever had a blood clot (DVT or pulmonary embolism) or breast cancer, as it can increase the risk of recurrence or further clots.

Intact uterus (womb)

If you still have your womb, you must also take a progestogen medicine alongside Oestrogel to prevent the lining of the womb from thickening excessively, which increases the risk of cancer.

Autoimmune diseases

Ashwagandha can stimulate the immune system, which may cause autoimmune conditions such as lupus, rheumatoid arthritis, and MS to flare up or become more active.

Food and drink warnings

Alcohol

It is best to avoid or strictly limit alcohol while using Oestrogel. Ashwagandha may increase the sedative effects of alcohol, making you feel more drowsy or uncoordinated than usual. It is best to avoid or limit alcohol while taking this supplement.

Alcohol can increase the levels of oestrogen in your blood, which may increase the risk of side effects. Additionally, long-term heavy drinking can damage the liver, affecting how your body processes this medication.

Grapefruit juice

Grapefruit and grapefruit juice can interfere with how your body breaks down oestrogen. This may lead to higher levels of the hormone in your blood, potentially increasing the risk of side effects.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.