Can I take Ashwagandha and Oestrogel pump-pack /actuation together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
Ashwagandha may increase the levels of oestrogen in your body, potentially making the effects of your Oestrogel stronger than intended. It might also interfere with how your body naturally balances hormones.
In this article:
Continue reading below
Why this happens
Ashwagandha is thought to have 'pro-oestrogenic' properties, meaning it may stimulate oestrogen receptors or increase the production of precursors to oestrogen. When used with Hormone Replacement Therapy (HRT) like Oestrogel, this could lead to an additive effect, resulting in higher-than-normal oestrogen activity.
What you should do
You should consult your doctor or a pharmacist before combining ashwagandha with Oestrogel. If you decide to use both, monitor yourself closely for signs of too much oestrogen, such as breast tenderness, bloating, headaches, or mood swings. Your doctor may need to monitor your hormone levels more frequently.
Continue reading below
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Treatment and medication
Can I take Evana heavy period relief and Mefenamic acid together?
Taking these two medicines together significantly increases your risk of serious stomach problems, such as stomach ulcers, bleeding, or irritation of the stomach lining. It can also put extra strain on your kidneys.

Treatment and medication
Can I take Atorvastatin and Flecainide together?
There is no known direct interaction between atorvastatin and flecainide. Both medications can be taken together safely in most cases.
Continue reading below
Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.