Can I take Aspirin 300 and Sertraline together?

Why this happens

Sertraline belongs to a group of antidepressants (SSRIs) that can lower the amount of serotonin in your blood platelets, which are the cells responsible for clotting. Aspirin also thins the blood by preventing these platelets from sticking together. When used together, their effects combine, making it much harder for your blood to clot if a blood vessel is damaged.

What you should do

You should only take these two medicines together if your doctor has specifically told you to. If you must take both, watch out for signs of bleeding such as unusual bruising, nosebleeds, or dark stools. If you experience severe stomach pain or vomit blood (which may look like coffee grounds), seek medical help immediately. Your doctor may suggest taking a 'stomach protector' medicine (like omeprazole) to reduce the risk of ulcers.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.