Can I take Aspirin and Desflurane together?
Drug interaction guide
Originally published 14 Mar 2026
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Taking aspirin and desflurane together can increase the risk of bleeding during and after surgery. Both substances affect how your blood clots, which can lead to more bruising or heavier bleeding than usual.
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Why this happens
Aspirin works by making the 'platelets' in your blood less sticky to prevent clots. Desflurane, an anaesthetic gas, can also interfere with how these platelets clump together. When used at the same time, their combined effect makes it much harder for your blood to clot properly.
What you should do
Back to contentsIf you are scheduled for surgery, it is vital to tell your surgeon and anaesthetist that you are taking aspirin. They may ask you to stop taking aspirin several days before your procedure to reduce the risk of bleeding. Do not stop taking prescribed aspirin without consulting your doctor first.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Treatment and medication
Can I take Acetaminophen and Trazodone together?
Taking paracetamol (acetaminophen) and trazodone together is generally considered safe, but there is a small risk of increased side effects. Both substances are processed by the liver, and in some cases, taking them together might slightly increase the levels of trazodone in your blood. This could make you feel more drowsy or dizzy than usual. Additionally, both medications can occasionally affect your liver function, so using them together over a long period requires caution.
Treatment and medication
Can I take Desmopressin and Ketoconazole together?
Taking these two medicines together can significantly increase the amount of desmopressin in your blood. This can lead to your body holding onto too much water, which can cause a dangerous drop in your blood salt levels (hyponatraemia). Symptoms to watch for include severe headache, nausea, vomiting, confusion, or feeling very drowsy.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published
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