Can I take Atenolol and Co-amoxiclav together?

Why this happens

Atenolol is a beta-blocker used for heart conditions and blood pressure, while co-amoxiclav is a combination antibiotic (amoxicillin and clavulanic acid). They are processed by the body through different pathways and do not interfere with how the other works.

You can take both medications as prescribed. However, if you have an infection (the reason for taking the antibiotic), your heart rate or blood pressure might naturally change. If you feel unusually dizzy or unwell, consult your doctor. Always complete the full course of antibiotics.

Asthma or COPD

Do not take atenolol if you have asthma or a history of wheezing. It can cause severe narrowing of the airways, making it very difficult to breathe.

Penicillin allergy

Do not take co-amoxiclav if you have ever had an allergic reaction to penicillin or similar antibiotics. A severe, life-threatening reaction (anaphylaxis) can occur.

Previous liver problems with co-amoxiclav

Do not take this medicine if you have previously developed jaundice (yellowing of the skin/eyes) or liver problems while taking co-amoxiclav or penicillin.

Alcohol

Drinking alcohol can increase the blood pressure-lowering effect of atenolol, which may make you feel dizzy or light-headed. It is best to limit alcohol intake, especially when starting the medicine or changing the dose.

Orange juice and Apple juice

Drinking large amounts of orange or apple juice may reduce the amount of atenolol absorbed by your body, making it less effective. Try to avoid drinking these juices within 2 hours of taking your tablet.

Food (General)

While not an interaction that stops the medicine working, co-amoxiclav is best taken at the start of a meal. This helps to prevent stomach upset and improves how the medicine is absorbed.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.