Can I take Atorvastatin and Rybelsus together?

Why this happens

Atorvastatin is a statin used to lower cholesterol, primarily processed by the liver (CYP3A4 enzyme). Rybelsus is a GLP-1 receptor agonist used for blood sugar control. While Rybelsus slows down how quickly the stomach empties, it has not been shown to significantly change how the body absorbs or processes atorvastatin.

What you should do

You can safely take these medications together as prescribed by your doctor. However, because Rybelsus can cause nausea or vomiting when you first start it, monitor yourself for any unusual muscle pain or weakness (a rare side effect of atorvastatin), as dehydration from vomiting can sometimes increase the risk of muscle issues. Always follow the specific dosing instructions for Rybelsus, which must be taken on an empty stomach with a small sip of plain water.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.