Can I take Lixiana and Solifenacin together?
Drug interaction guide
Originally published 25 Jan 2026
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There is no known direct interaction between Lixiana (edoxaban) and solifenacin. Taking these two medicines together is generally considered safe.
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Why this happens
Lixiana is an anticoagulant (blood thinner) that works by blocking a specific clotting factor in the blood. Solifenacin is an antimuscarinic used to treat overactive bladder by relaxing the bladder muscles. These drugs are processed by different pathways in the body and do not interfere with how the other works.
What you should do
You can take these medicines together as prescribed by your doctor. However, always watch for general side effects. If you notice unusual bruising or bleeding (linked to Lixiana) or severe constipation and dry mouth (linked to solifenacin), consult your healthcare professional.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published
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