Can I take Losartan and Vitamin d together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
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There is no known direct interaction between losartan and vitamin D supplements. Taking these two together is generally considered safe.
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Why this happens
Losartan is a blood pressure medication (angiotensin II receptor blocker) and vitamin D is a fat-soluble vitamin. They are processed by different pathways in the body and do not interfere with each other's effectiveness or safety.
What you should do
You can continue to take both as prescribed. It is always a good idea to have your blood pressure and kidney function monitored regularly by your doctor while taking losartan, regardless of vitamin D use.
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Important precautions
Pregnancy
You must not take losartan if you are pregnant or planning to become pregnant. It can cause serious harm or death to an unborn baby, particularly if used in the second and third trimesters.
High potassium levels (Hyperkalaemia)
Losartan can increase potassium levels in your blood. Avoid using salt substitutes containing potassium or taking potassium supplements unless specifically told to by your doctor.
Food and drink warnings
Potassium-rich foods (e.g., bananas, spinach, avocados) and salt substitutes
Losartan can increase the levels of potassium in your blood. Consuming large amounts of potassium-rich foods or using salt substitutes containing potassium can lead to dangerously high potassium levels (hyperkalaemia).
Alcohol
Drinking alcohol while taking losartan can increase the medicine's blood-pressure-lowering effect. This may make you feel dizzy, lightheaded, or faint, especially when standing up.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published
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