Can I take Maitake and Turkey tail together?

Why this happens

Both maitake (Grifola frondosa) and turkey tail (Trametes versicolor) contain complex sugars called beta-glucans. These compounds work in a similar way by activating certain immune cells (like natural killer cells and macrophages). Taking them together may increase this immune-stimulating effect.

What you should do

It is generally considered safe to take these two supplements together. However, if you have an autoimmune condition (such as lupus or rheumatoid arthritis) or are taking immunosuppressant medication, you should consult your doctor before combining them, as they may interfere with your treatment. Always start with the recommended dose on the product packaging.

Important precautions

Bleeding disorders or surgery

These supplements may slow blood clotting and increase the risk of bleeding. You must stop taking these at least 2 weeks before any scheduled surgery. Use with caution if you are taking blood-thinning medications like warfarin or aspirin.

Diabetes

These supplements can lower blood sugar levels. If you are taking insulin or other diabetes medications, monitor your blood sugar closely as your dose may need adjustment to prevent hypoglycaemia (dangerously low blood sugar).

Low blood pressure (Hypotension)

These supplements may lower blood pressure. If you already have low blood pressure or take medication to control high blood pressure, they could cause your blood pressure to drop too low.

Food and drink warnings

Alcohol

It is best to avoid or strictly limit alcohol when taking medicinal mushrooms. Both alcohol and certain compounds in these mushrooms are processed by the liver; combining them may increase the strain on your liver or alter how the supplements are metabolised.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.