Can I take Atorvastatin and Tamsulosin together?
Drug interaction guide
Originally published 25 Jan 2026
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There is no known direct interaction between atorvastatin and tamsulosin. It is generally considered safe to take these two medications together.
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Why this happens
Atorvastatin and tamsulosin are processed by different pathways in the body and do not interfere with how the other drug works or is cleared from your system.
What you should do
Back to contentsYou can continue taking both medications as prescribed by your doctor. As with any medication, if you notice any unusual side effects like unexplained muscle pain (related to the statin) or feeling very dizzy when standing up (related to the tamsulosin), you should mention this to your GP or pharmacist.
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Important precautions
Back to contentsPregnancy
You must not take atorvastatin if you are pregnant or planning to become pregnant, as it can cause serious harm to an unborn baby. Use effective contraception while taking this medicine.
Muscle disorders - atorvastatin
Seek immediate medical advice if you experience unexplained muscle pain, tenderness, or weakness. In rare cases, this can lead to a serious condition called rhabdomyolysis which causes kidney damage.
Cataract surgery
If you are due to have eye surgery for cataracts or glaucoma, you must tell your eye surgeon you are taking tamsulosin, as it can cause a complication called 'Floppy Iris Syndrome'.
Food and drink warnings
Back to contentsGrapefruit juice
Grapefruit juice contains compounds that can increase the level of atorvastatin in your blood. This may increase your risk of side effects, such as muscle pain or damage. Avoid drinking large quantities (more than 1.2 litres per day), though it is safest to avoid it altogether or keep intake to very small amounts.
Alcohol
While alcohol does not directly interact with atorvastatin, drinking large amounts of alcohol can increase the risk of liver problems and muscle side effects. It is best to keep your intake within the recommended limits (no more than 14 units per week).
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Treatment and medication
Can I take Atorvastatin and Colecalciferol together?
Taking atorvastatin and colecalciferol (Vitamin D3) together is generally safe and may even be beneficial. Some studies suggest that Vitamin D can slightly lower the levels of atorvastatin in your blood, but this rarely affects how well the medicine works to lower your cholesterol. Conversely, atorvastatin may actually help increase your Vitamin D levels.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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