Can I take Bronco cough medicine and Serlan together?

Why this happens

Serlan (sertraline) is an SSRI antidepressant that increases serotonin levels. Bronco cough medicine contains dextromethorphan, which also slightly increases serotonin. When combined, they can raise serotonin to unsafe levels. Furthermore, both medicines can have a calming effect on the central nervous system, leading to increased sleepiness.

What you should do

You should speak to your doctor or pharmacist before taking these together. They may suggest a different type of cough medicine that does not contain dextromethorphan (such as a simple linctus or a medicine containing only guanifenesin). If you are already taking both and feel very unwell, confused, or have a high fever, seek medical help immediately.

Important precautions

Bleeding disorders or use of blood thinners

Serlan can increase your risk of serious bleeding, especially if you are also taking aspirin, ibuprofen, or blood-thinning medications like warfarin.

Bipolar disorder or history of mania

This medicine can trigger a manic episode (extreme high mood and overactivity) in people with undiagnosed bipolar disorder.

Serotonin Syndrome risk

Check with a pharmacist before using certain cough suppressants (like dextromethorphan) with Serlan, as the combination can cause a life-threatening reaction called serotonin syndrome.

Food and drink warnings

Alcohol

You should avoid drinking alcohol while taking Serlan. Combining alcohol with this medicine can increase side effects like drowsiness, dizziness, and impaired concentration.

Grapefruit juice

Avoid consuming large amounts of grapefruit juice. Grapefruit can increase the levels of sertraline in your blood, which may increase the risk of side effects.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.