Can I take Candesartan cilexetil and Eplerenone together?

Why this happens

Both candesartan and eplerenone work by affecting a hormone system in the body that regulates salt and water balance. Specifically, they both cause the kidneys to keep hold of potassium rather than flushing it out in the urine. When used together, this 'potassium-sparing' effect is doubled.

What you should do

You must speak to your doctor before taking these together. If prescribed both, your doctor will need to monitor your kidney function and potassium levels very closely with regular blood tests. Seek medical help immediately if you experience muscle weakness, tingling sensations, or an irregular heartbeat. Avoid using salt substitutes containing potassium (such as Lo-Salt) while taking these medicines.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.