Can I take Candesartan and Rosuvastatin together?

Why this happens

Candesartan and rosuvastatin are processed by different pathways in the body. Candesartan is mainly excreted unchanged, while rosuvastatin is processed by specific liver enzymes that do not interfere with how candesartan works. They do not compete for absorption or elimination.

What you should do

You can safely take these two medicines together as prescribed by your doctor. You do not need to separate the doses or change your routine. As with all cholesterol-lowering 'statin' medicines, contact your doctor if you experience any unexplained muscle pain, tenderness, or weakness.

Important precautions

Pregnancy

You must not take candesartan if you are pregnant or planning to become pregnant. It can cause serious harm or death to an unborn baby, especially if used during the second and third trimesters.

You must not take rosuvastatin if you are pregnant or trying to conceive, as it may harm the developing baby. Use effective contraception while taking this medicine and stop immediately if you become pregnant.

Unexplained muscle pain or weakness - rosuvastatin

Contact your doctor immediately if you experience unexplained muscle pain, tenderness, or weakness. In rare cases, statins can cause severe muscle breakdown which can lead to kidney damage.

Food and drink warnings

Alcohol

Drinking alcohol while taking candesartan can increase the blood-pressure-lowering effect of the medicine. This may make you feel dizzy, lightheaded, or faint, especially when standing up. It is best to keep your alcohol intake within recommended limits and see how the medicine affects you before drinking.

You should limit your alcohol intake while taking rosuvastatin. Drinking large amounts of alcohol regularly or binge drinking can increase your risk of serious muscle problems and liver damage.

Potassium-rich foods (e.g., bananas, spinach, salt substitutes)

Candesartan can increase the levels of potassium in your blood. Consuming large amounts of foods very high in potassium or using potassium-based salt substitutes (such as Lo-Salt) can lead to dangerously high potassium levels (hyperkalaemia). You should avoid using potassium-based salt substitutes unless advised otherwise by your doctor.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.