Can I take Candesartan cilexetil and Rosuvastatin together?

Why this happens

Candesartan and rosuvastatin are processed by different pathways in the body. Candesartan is mainly excreted unchanged, while rosuvastatin is processed by specific liver enzymes that do not interfere with how candesartan works. They do not compete for absorption or elimination.

What you should do

You can safely take these two medicines together as prescribed by your doctor. You do not need to separate the doses or change your routine. As with all cholesterol-lowering 'statin' medicines, contact your doctor if you experience any unexplained muscle pain, tenderness, or weakness.

Important precautions

Pregnancy

You must not take these medicines if you are pregnant or planning to become pregnant. Candesartan can cause serious harm to an unborn baby, and Rosuvastatin is essential for foetal development and must be stopped at least one month before trying to conceive.

Unexplained muscle pain

You must contact your doctor immediately if you experience any unexplained muscle pain, tenderness, or weakness. In rare cases, this can lead to a serious condition called rhabdomyolysis which causes kidney damage.

High potassium levels (Hyperkalaemia)

Avoid using salt substitutes containing potassium or taking potassium supplements while on this medicine, as it can cause your blood potassium levels to become dangerously high.

Food and drink warnings

Alcohol

You should limit your alcohol intake while taking rosuvastatin. Drinking large amounts of alcohol regularly or binge drinking can increase your risk of serious muscle problems and liver damage.

Salt substitutes (Potassium-based)

Avoid using salt substitutes that contain potassium (such as Lo-Salt). Candesartan can increase the levels of potassium in your blood. Using these substitutes alongside your medicine can lead to dangerously high potassium levels (hyperkalaemia).

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.