Can I take Celebrex and Sulfasalazine together?

Why this happens

Both drugs can reduce the production of prostaglandins, which are natural chemicals that help protect the lining of the stomach and maintain blood flow to the kidneys. When used together, their effects on the kidneys can be additive, potentially leading to reduced kidney function or fluid retention.

You should only take these two medications together if they have been specifically prescribed by your doctor. Your doctor may want to monitor your kidney function with regular blood tests. Ensure you stay well-hydrated by drinking plenty of water. If you notice swelling in your ankles, a significant change in how often you urinate, or severe stomach pain, contact your doctor immediately.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.