Can I take Chaga and Shiitake together?

Why this happens

Both mushrooms contain compounds that can slow down blood clotting (antiplatelet effects) and improve how the body handles insulin, leading to an additive effect when combined.

What you should do

It is generally safe to eat these as part of a normal diet. However, if you are taking concentrated supplements, monitor your blood sugar levels closely (if diabetic) and watch for signs of easy bruising or bleeding. Consult your doctor before combining these supplements if you are scheduled for surgery or are taking blood-thinning medications like warfarin.

Important precautions

Kidney disease or history of kidney stones

Chaga is extremely high in oxalates, which can cause permanent kidney damage or acute kidney failure, especially in those with existing renal issues.

Diabetes

Both mushrooms may significantly lower blood sugar levels, increasing the risk of hypoglycaemia (dangerously low blood sugar) if you are taking insulin or other diabetes medications.

Autoimmune diseases (e.g., Lupus, MS, Rheumatoid Arthritis)

Chaga can stimulate the immune system, which may worsen symptoms of autoimmune conditions or interfere with immunosuppressant medications.

Bleeding disorders or upcoming surgery

Both mushrooms can significantly thin the blood and increase the risk of bleeding. You must stop taking them at least 2 weeks before any planned surgery.

Shiitake dermatitis

Eating raw or undercooked shiitake can cause a severe, itchy, whip-like skin rash (shiitake flagellate dermatitis) that can last for weeks. Always cook shiitake thoroughly.

Food and drink warnings

Alcohol

Chaga contains high levels of oxalates. Combining it with alcohol may increase the risk of kidney stones or kidney stress, as both substances can affect renal function. Use with caution.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.