Can I take Chaga and White button together?
Drug interaction guide
Originally published 25 Jan 2026
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There are no known harmful interactions between chaga mushrooms and white button mushrooms. Both are edible fungi that are generally safe to consume together as part of a balanced diet.
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Why this happens
Chaga (Inonotus obliquus) and white button mushrooms (Agaricus bisporus) do not share metabolic pathways or chemical compounds that would cause a negative reaction when combined. Both contain various antioxidants and polysaccharides (like beta-glucans), but these do not interfere with one another.
What you should do
Back to contentsYou can safely consume these together. However, if you are taking chaga as a concentrated supplement, ensure you follow the dosage instructions on the label. If you have a known mushroom allergy, avoid both.
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Important precautions
Back to contentsKidney disease or history of kidney stones
Chaga is extremely high in oxalates, which can cause permanent kidney damage or acute kidney failure, especially in those with existing renal issues.
Diabetes
Chaga may significantly lower blood sugar levels, increasing the risk of hypoglycaemia (dangerously low blood sugar) if you are taking insulin or other diabetes medications.
Autoimmune diseases (e.g., Lupus, MS, Rheumatoid Arthritis)
Chaga can stimulate the immune system, which may worsen symptoms of autoimmune conditions or interfere with immunosuppressant medications.
Bleeding disorders or upcoming surgery
Chaga may slow blood clotting and increase the risk of bleeding; it should be avoided if you have a bleeding disorder or are scheduled for surgery.
Food and drink warnings
Back to contentsAlcohol
Chaga contains high levels of oxalates. Combining it with alcohol may increase the risk of kidney stones or kidney stress, as both substances can affect renal function. Use with caution.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published
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