Can I take Lion's mane and Matcha together?

Why this happens

Lion's Mane is thought to stimulate 'nerve growth factor' (NGF) to support brain health, while matcha contains caffeine and L-theanine which improve alertness and focus. There is no evidence that they interfere with how the body absorbs or breaks down the other.

What you should do

It is generally safe to take these together. If you are sensitive to caffeine, monitor for jitters or a racing heart. If you have an upcoming surgery, stop taking Lion's Mane at least two weeks prior as it may slightly thin the blood.

Important precautions

Bleeding disorders or surgery

Both matcha and lion's mane may slow blood clotting. This can increase the risk of bruising and bleeding, and may cause complications during or after surgical procedures. Stop use at least 2 weeks before scheduled surgery.

Food and drink warnings

Alcohol

It is best to avoid or strictly limit alcohol when taking Lion's Mane. While there is limited clinical data on the specific interaction, both substances can affect the central nervous system. Combining them may increase the risk of drowsiness or dizziness. Additionally, alcohol can cause inflammation that may counteract the potential neuroprotective benefits of the supplement.

It is best to avoid or strictly limit alcohol when consuming matcha. Both substances can affect your liver, and combining them may increase the risk of liver strain. Additionally, the caffeine in matcha can mask the sedative effects of alcohol, which may lead you to drink more than intended.

Dairy products (Milk)

Adding milk to matcha may reduce the absorption of beneficial antioxidants (catechins) into your bloodstream. If you are drinking matcha for its health benefits, you may wish to consume it without dairy.

Foods high in Vitamin K (Leafy greens)

Matcha contains high levels of Vitamin K. If you are taking blood-thinning medication like warfarin, you must keep your intake of matcha consistent, as sudden changes can interfere with how your medication works.

Caffeine

Matcha is very high in caffeine. You should be cautious about consuming other caffeinated drinks (like coffee or energy drinks) alongside it, as this can lead to jitteriness, increased heart rate, and difficulty sleeping.

Iron-rich foods

The tannins in matcha can bind to iron from plant-based foods (non-heme iron), making it harder for your body to absorb. It is best to drink matcha between meals rather than with them if you have low iron levels.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.