Can I take Colecalciferol and Doxazosin together?

Why this happens

Colecalciferol is a vitamin used to maintain calcium levels and bone health, while doxazosin is an alpha-blocker used to treat high blood pressure or an enlarged prostate. They are processed by different pathways in the body and do not interfere with each other's effectiveness or safety.

You can continue to take both medications as prescribed by your doctor. No special precautions or monitoring are required specifically for this combination.

First-dose hypotension

Doxazosin can cause a sudden, large drop in blood pressure when you first start taking it or when the dose is increased. This can make you feel very dizzy or faint. Take your first dose at bedtime and be careful when getting out of bed.

Hypercalcaemia (high blood calcium)

Do not take colecalciferol if you have high levels of calcium in your blood or urine, or if you have severe kidney stones, as vitamin D increases calcium absorption and can worsen these conditions.

Cataract surgery (Intraoperative Floppy Iris Syndrome)

If you are planning to have eye surgery for cataracts, you must tell your eye surgeon that you are taking or have previously taken doxazosin. It can cause the iris to become 'floppy' during the procedure, which may lead to complications unless the surgeon is prepared.

Alcohol

It is best to avoid or strictly limit alcohol while taking colecalciferol. Long-term heavy alcohol use can interfere with how your body absorbs and processes Vitamin D, making the treatment less effective.

It is best to avoid or strictly limit alcohol while taking doxazosin. Doxazosin lowers your blood pressure, and alcohol can increase this effect, making you feel dizzy, lightheaded, or faint, especially when standing up.

High-fat meals

Colecalciferol is a fat-soluble vitamin. It is best absorbed by your body when taken with a meal that contains some fat (such as eggs, avocado, nuts, or dairy).

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.