Can I take Colecalciferol and Pregabalin together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
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There are no known significant interactions between colecalciferol and pregabalin. It is generally considered safe to take these two medications together.
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Why this happens
Colecalciferol (Vitamin D3) and pregabalin are processed by the body through different pathways. Colecalciferol is a fat-soluble vitamin involved in calcium regulation, while pregabalin works on specific calcium channels in the nervous system to treat pain or anxiety. They do not interfere with each other's absorption, breakdown, or effectiveness.
What you should do
You can continue to take both medications as prescribed by your doctor. No special precautions or timing adjustments are necessary for this combination.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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