Can I take Devil's claw and Evening primrose oil together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
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Taking devil's claw and evening primrose oil together may increase your risk of bruising or bleeding. This is because both supplements can thin the blood or slow down the clotting process. While the risk is generally low for healthy individuals, it is more significant if you are already taking blood-thinning medications or have an upcoming surgery.
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Why this happens
Both supplements have 'antiplatelet' effects. This means they make the tiny cells in your blood (platelets) less 'sticky', which makes it harder for your blood to form clots. When used together, this effect is added together (an additive effect).
What you should do
You should use this combination with caution. Watch for signs of unusual bleeding, such as bleeding gums, nosebleeds, or easy bruising. If you are scheduled for any surgery or dental work, stop taking both supplements at least two weeks before the procedure. Consult your doctor before combining these if you take blood-thinning medicines like warfarin, aspirin, or clopidogrel.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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