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Can I take Evening primrose oil and Vitamin c together?

Drug interaction guide

There are no known significant interactions between evening primrose oil and vitamin C. It is generally considered safe to take these two supplements together.

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Why this happens

Evening primrose oil is a source of omega-6 fatty acids (specifically gamma-linolenic acid), while vitamin C is a water-soluble antioxidant. They are processed by the body through different pathways and do not interfere with each other's absorption, metabolism, or effectiveness. In fact, some evidence suggests that antioxidants like vitamin C may help protect the fatty acids in evening primrose oil from oxidising (breaking down) in the body.

What you should do

You can continue to take both supplements as directed. As with any supplement, it is best to take them with food to reduce the chance of an upset stomach. If you have any underlying health conditions or are taking prescribed medications (especially blood thinners or epilepsy medication), consult your pharmacist or doctor before starting new supplements.

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Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 25 Jan 2026 | Originally published
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