Can I take Flecainide and Tamsulosin together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
Taking flecainide and tamsulosin together may increase the levels of tamsulosin in your blood. This can make you more likely to experience side effects such as dizziness, lightheadedness, or a sudden drop in blood pressure when you stand up (fainting).
In this article:
Continue reading below
Why this happens
Both drugs are processed by the same enzyme in the liver (CYP2D6). Flecainide can slow down this enzyme, which prevents tamsulosin from being broken down as quickly as usual, leading to higher levels of the drug in your system.
What you should do
You can take these medicines together, but you should be cautious. Monitor your blood pressure and watch for signs of dizziness, especially when moving from a sitting or lying position to standing. If you feel very dizzy or faint, contact your doctor, as they may need to adjust your tamsulosin dose.
Continue reading below
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Treatment and medication
Can I take Magnesium and Bisoprolol together?
Taking magnesium and bisoprolol together can lead to an excessively slow heart rate or a significant drop in blood pressure. This may cause you to feel dizzy, lightheaded, or faint.

Treatment and medication
Can I take Clarithromycin and Rosuvastatin together?
Taking these two medicines together can significantly increase the amount of rosuvastatin in your blood. This increases the risk of serious muscle damage (rhabdomyolysis), which can lead to kidney problems. Symptoms to watch for include unexplained muscle pain, tenderness, or weakness, especially if you also feel generally unwell or have a fever.
Continue reading below
Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.